July 31, 2026

Secukinumab Trial Targets Relapsed Polymyalgia Rheumatica

Phase 3 findings address remission durability and glucocorticoid use in patients who relapsed during prednisone tapering.

MDSpire News

July 29, 2026

Can Statin Muscle Risk Be Predicted?

Researchers developed and externally validated a prediction model estimating 1-, 5-, and 10-year risks of serious muscle disorders among patients potentially eligible for statin therapy.

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July 29, 2026

Bearing Combinations May Improve THA Survival

A linked UK registry analysis found lower long-term reoperation rates with select highly crosslinked polyethylene bearing combinations following total hip arthroplasty.

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July 24, 2026

May Kaplan Fiber Injury Signal Greater Knee Instability?

Magnetic resonance imaging showed that Kaplan fiber injury was associated with greater anterior tibial subluxation following anterior cruciate ligament injury, suggesting that the finding may help identify patients with greater knee instability.

MDSpire News

July 23, 2026

GRAPPA, EULAR Criteria May Identify Complex PsA

Application of newly proposed GRAPPA and EULAR criteria in a longitudinal cohort identified progressively smaller groups of patients with early psoriatic arthritis who experienced persistently worse patient-reported outcomes.

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July 22, 2026

Ixekizumab May Improve Early Response After Secukinumab Failure

A real-world cohort found faster early skin responses with ixekizumab than with guselkumab or ustekinumab following secukinumab treatment failure, while all three biologics demonstrated favorable safety.

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July 22, 2026

Medical Oddities: When AI Meets the Afterlife

Ghosts, germs, B cells, and brews—this week's research is anything but ordinary.

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July 20, 2026

Tenderness Tracks Ultrasound Findings

Joint tenderness showed broader associations with concurrent ultrasound abnormalities than patient-reported pain among anti-cyclic citrullinated peptide–positive patients without clinical arthritis.

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July 15, 2026

Joint Site May Influence RA Treatment Response

A Swiss registry study found that the wrist and second and third metacarpophalangeal joints consistently resolved more slowly than most other joints following biologic or targeted synthetic therapy.

MDSpire News

July 15, 2026

Serostatus May Modify RA Activity–CV Link

Combined rheumatoid factor and anticitrullinated protein antibody status appeared to modify the association between baseline rheumatoid arthritis disease activity and subsequent cardiovascular events in an international observational cohort.

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