July 31, 2026

Secukinumab Trial Targets Relapsed Polymyalgia Rheumatica

Phase 3 findings address remission durability and glucocorticoid use in patients who relapsed during prednisone tapering.

MDSpire News

July 29, 2026

Bearing Combinations May Improve THA Survival

A linked UK registry analysis found lower long-term reoperation rates with select highly crosslinked polyethylene bearing combinations following total hip arthroplasty.

MDSpire News

July 23, 2026

GRAPPA, EULAR Criteria May Identify Complex PsA

Application of newly proposed GRAPPA and EULAR criteria in a longitudinal cohort identified progressively smaller groups of patients with early psoriatic arthritis who experienced persistently worse patient-reported outcomes.

MDSpire News

July 20, 2026

Tenderness Tracks Ultrasound Findings

Joint tenderness showed broader associations with concurrent ultrasound abnormalities than patient-reported pain among anti-cyclic citrullinated peptide–positive patients without clinical arthritis.

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July 15, 2026

Joint Site May Influence RA Treatment Response

A Swiss registry study found that the wrist and second and third metacarpophalangeal joints consistently resolved more slowly than most other joints following biologic or targeted synthetic therapy.

MDSpire News

July 15, 2026

Serostatus May Modify RA Activity–CV Link

Combined rheumatoid factor and anticitrullinated protein antibody status appeared to modify the association between baseline rheumatoid arthritis disease activity and subsequent cardiovascular events in an international observational cohort.

MDSpire News

July 07, 2026

More Physicians Enter Politics

Viewpoint explores how more physician-candidates could reshape both public service and public trust in medicine.

MDSpire News

July 06, 2026

Does TYK2/JAK1 Show Potential in Inflammatory Diseases?

Investigational inhibitor was not associated with treatment-related serious adverse events and produced biomarker changes consistent with pathway inhibition in healthy volunteers.

MDSpire News

July 02, 2026

Transdermal NSAID Matches Oral Celecoxib After Knee Replacement

Randomized trial finds a topical anti-inflammatory patch provided similar pain relief, function, and safety as oral therapy during the first 6 weeks after surgery.

MDSpire News

July 01, 2026

NEJM Retracts Avacopan Vasculitis Study

"The primary end-point assessments in nine patients were readjudicated after database lock and trial unblinding"

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