September 08, 2026

CD19 CAR T Therapy Tested in Refractory Rheumatoid Arthritis

Disease activity fell in all six participants in a phase I trial, with three achieving sustained drug-free remission during follow-up

The Medicine Maker

August 31, 2026

Emergency diagnosis may flag poor outcomes beyond cancer

Across 13 noncancer conditions, emergency diagnosis was common and associated with higher 1-year mortality.

MDSpire News

August 21, 2026

Sex-based differences in hip replacement outcomes

A systematic review of more than 2.3 million patients found that women and men had different patterns of postoperative complications and recovery, with age and implant strategy modifying observed differences.

MDSpire News

August 21, 2026

Rheumatoid arthritis tied to birth outcomes

Researchers examine pregnancy outcomes and factors associated with preterm delivery and fetal size.

MDSpire News

August 17, 2026

Does Poor Oral Health Raise Autoimmune Disease Risk?

A study of more than 450,000 participants linked self-reported oral health issues with an increased risk of incident autoimmune diseases, though the investigators cautioned that the findings do not establish causality.

MDSpire News

August 17, 2026

Does Poor Oral Health Raise Autoimmune Disease Risk?

A study of more than 450,000 participants linked self-reported oral health issues with an increased risk of incident autoimmune diseases, though the investigators cautioned that the findings do not establish causality.

MDSpire News

July 20, 2026

Tenderness Tracks Ultrasound Findings

Joint tenderness showed broader associations with concurrent ultrasound abnormalities than patient-reported pain among anti-cyclic citrullinated peptide–positive patients without clinical arthritis.

MDSpire News

July 15, 2026

Joint Site May Influence RA Treatment Response

A Swiss registry study found that the wrist and second and third metacarpophalangeal joints consistently resolved more slowly than most other joints following biologic or targeted synthetic therapy.

MDSpire News

July 15, 2026

Serostatus May Modify RA Activity–CV Link

Combined rheumatoid factor and anticitrullinated protein antibody status appeared to modify the association between baseline rheumatoid arthritis disease activity and subsequent cardiovascular events in an international observational cohort.

MDSpire News

July 06, 2026

Does TYK2/JAK1 Show Potential in Inflammatory Diseases?

Investigational inhibitor was not associated with treatment-related serious adverse events and produced biomarker changes consistent with pathway inhibition in healthy volunteers.

MDSpire News