Low-dose lipopolysaccharide and fungal airway exposure were linked to persistent airway hyperresponsiveness despite glucocorticoid treatment in experimental models.
Combining IL-17 with TNF-alpha showed strong discrimination between carious lesions and healthy controls, but performance was more modest against gingival inflammation.
A combination of PSA density, MRI, and PSMA PET findings identified a small subgroup with adverse pathology, supporting further study of biopsy-sparing pathways.
Investigators compared intra-articular microbial profiles and predicted metabolic pathways in patients with hip osteoarthritis and nonarthritic controls.
Automated lesion measurements increased agreement on treatment response, although expert-generated proposals were accepted more often and required fewer adjustments.
Women reported improvement across 6 cognitive domains during 12 months of estriol-based treatment, while murine models suggested a potential astrocyte-mediated mechanism.
A 20-minute exercise bout and 90-minute nap produced similar episodic memory performance following 30 hours of wakefulness but engaged distinct neural mechanisms.