October 28, 2026

NUT carcinoma may defy typical staining patterns

Two pulmonary cases highlight how limited squamous differentiation and variable keratin expression may complicate pathological diagnosis.

MDSpire News

October 26, 2026

Cryptococcal cellulitis may lead to amputation

A splinter injury progressed to finger necrosis in a patient with MDS, despite antibacterial treatment and no clinically apparent systemic dissemination.

MDSpire News

October 15, 2026

AI may predict focal GBM recurrence

Optical analysis of resection-margin tissue identified tumor infiltration as the strongest contributor to predictions of where glioblastoma later recurred.

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October 05, 2026

Rare GI disease leads to 20-plus units of transfused blood

A rare intestinal lymphangioma caused life-threatening bleeding without typical laboratory features of protein-losing enteropathy

MDSpire News

September 25, 2026

FDA monthly preview: Key October decisions to watch

Several FDA decisions across multiple specialties are expected this month.

MDSpire News

September 24, 2026

FDA approves combo for advanced renal cell carcinoma

Median progression-free survival was 15 months with the combination vs. 11 months with cabozantinib in the LITESPARK-011 trial.

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September 24, 2026

FDA clears targeted cholangiocarcinoma therapy

In the single-arm REFOCUS trial, 46% of patients responded to treatment, with a median response duration of 11.8 months.

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September 18, 2026

Retained silk may underlie late postvasectomy fistula

Surgery and histopathology identified retained silk ligature with chronic inflammation at the site of a rare fistula presenting 3 years following vasectomy.

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September 15, 2026

Photodynamic therapy gains FDA approval for superficial BCC

Phase 3 trial data showed greater clinical and histological clearance than with placebo photodynamic therapy.

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September 08, 2026

Triple-positive profile may flag adverse prostate cancer pathology

A combination of PSA density, MRI, and PSMA PET findings identified a small subgroup with adverse pathology, supporting further study of biopsy-sparing pathways.

MDSpire News