5 Key Takeaways

• 1

  Intermittent fasting shows little to no difference in weight loss compared to standard diets for adults with overweight or obesity.

• 2

  The Cochrane review analyzed 22 trials with 1995 participants, focusing on various intermittent fasting regimens.

• 3

  Intermittent fasting resulted in a mean weight difference of −0.33% from baseline, with low certainty due to bias concerns.

• 4

  Quality-of-life assessments revealed minimal differences between intermittent fasting and conventional dietary approaches.

• 5

  Adverse events were reported with intermittent fasting, but evidence on their frequency compared to standard diets was very uncertain.