5 Key Takeaways

• 1

  Spironolactone prescriptions among young women increased from 17 to 88 per 100,000 from 2000 to 2020.

• 2

  The highest increase in prescriptions was observed in women aged 19 to 25 years.

• 3

  Acne was the most common diagnosis among new spironolactone users, accounting for 55.5% of cases.

• 4

  29.4% of users had no recorded diagnosis for conditions typically treated with spironolactone.

• 5

  Further safety research is needed to evaluate high-dose spironolactone use in younger populations.