5 Key Takeaways

• 1

  The VA and DoD released a 2025 guideline for asthma management, emphasizing anti-inflammatory strategies over symptom-driven therapies.

• 2

  The updated guideline recommends inhaled corticosteroid-containing reliever strategies, moving away from short-acting beta-agonist-only therapy.

• 3

  Single-device maintenance and reliever therapy (SMART) significantly reduced severe asthma exacerbations by about one-third in trials.

• 4

  Management of comorbidities, such as obesity and gastroesophageal reflux disease, is highlighted to improve asthma control.

• 5

  The guideline suggests a combination of ICS and rapid-onset LABA for asthma control and relief, streamlining treatment approaches.