5 Key Takeaways

• 1

  Antiviral treatment significantly reduced hospitalization, ICU admission, and mortality in nonhospitalized patients with influenza.

• 2

  In a study of 426,275 patients, hospitalization rates were 1.54% for treated patients versus 1.70% for untreated patients.

• 3

  Oseltamivir showed consistent benefits across secondary outcomes, while baloxavir had fewer primary outcome events.

• 4

  Subgroup analyses indicated hospitalization reductions in both adult and pediatric patients, with regional variations noted.

• 5

  The study's limitations included potential confounding factors and incomplete documentation, necessitating cautious interpretation of results.