September 10, 2026

Gut-derived ImP may promote biliary injury

Higher ImP levels were associated with reduced transplant-free survival in PSC, while experimental models implicated p38 signaling in inflammation and fibrosis.

MDSpire News

September 04, 2026

Inside the hip osteoarthritis microbiome

Investigators compared intra-articular microbial profiles and predicted metabolic pathways in patients with hip osteoarthritis and nonarthritic controls.

MDSpire News

August 31, 2026

How does IBD relate to joint infection risk?

Investigators assessed 90-day outcomes among patients with IBD who underwent elective total joint arthroplasty.

MDSpire News

August 28, 2026

FDA approves bictegravir and lenacapavir for HIV

The treatment was evaluated in patients receiving complex antiretroviral regimens.

MDSpire News

August 20, 2026

Medical Oddities: Sheep wool gets into bone repair

From sheep wool to space guts, cannabis beats to tea: science took a wonderfully weird turn. 

MDSpire News

August 18, 2026

Top 10 evidence-based essentials in infectious disease

A structured framework of guidelines, trials, therapies, and tools used in clinical practice

MDSpire News

August 13, 2026

A Matter of Mosquito Taste

Behavioral testing, GC-MS, and microbiome profiling show that three mosquito species differ in which people they find attractive

The Analytical Scientist

July 23, 2026

Oral Shigella Vaccine Hits 89% Efficacy in Challenge Trial

An investigational oral Shigella sonnei vaccine showed robust protection against shigellosis in a phase 2 controlled human infection trial.

MDSpire News

July 08, 2026

Oral Microbiome Richness Tied to CRS

A cross-sectional metagenomic study found greater oral microbiome richness among adults with chronic rhinosinusitis, particularly nonallergic chronic rhinosinusitis, while associations with asthma, airway inflammation, and most lung-function measures were inconsistent.

MDSpire News

June 29, 2026

Side Effects: The Gut Goes Rogue

When fiber metabolism falters in lupus, the microbiome may start dining on the host instead. This week: mucin-munching bugs, brain-delivered DHA with no cognitive payoff, and lipid-loaded MS lesions that may not be innocent bystanders.

MDSpire News