Telomere Length May Signal Brain Disease Risk
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February 18, 2025
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Shorter telomeres may indicate increased risk for stroke, dementia, and late-life depression according to a study of over 356,000 individuals.
Individuals with the shortest telomeres showed an 8% higher risk of stroke, 19% higher risk of dementia, and 14% higher risk of late-life depression.
The study tracked participants for a median of 12 years and employed Mendelian randomization to explore causality.
Healthier lifestyle choices may mitigate risks associated with shorter telomeres, as indicated by higher Brain Care Scores.
The findings are preliminary and focus solely on participants of European ancestry, with limitations in measuring telomere length.
This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.
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