5 Key Takeaways

• 1

  The American College of Physicians recommends hormone therapy as the first-line treatment for menopausal vasomotor symptoms.

• 2

  Estrogen combined with a progestogen is recommended for patients with a uterus, while estrogen monotherapy is for those without.

• 3

  For patients intolerant to first-line therapy, the ACP conditionally recommends desvenlafaxine or venlafaxine as second-line treatments.

• 4

  The ACP advises using the lowest effective dose of estrogen and cautions about potential risks associated with hormone therapy.

• 5

  Most studies informing the guidelines involved generally healthy postmenopausal patients, limiting broader application of the recommendations.