Objective:

To evaluate the effectiveness of current transvaginal ultrasonography triage strategies for diagnosing endometrial cancer in Black patients.

Approach:

• Study Design: A retrospective diagnostic study merging electronic health record data and secondary administrative data from 1,494 Black individuals with a uterus.
• Data Collection Period: Data was collected from January 1, 2014, to December 31, 2020, with analysis conducted from January 31, 2023, to November 30, 2023.

Key Findings:

• 210 out of 1,494 Black patients were diagnosed with endometrial cancer.
• Common presenting diagnoses included fibroids (78.1%), vaginal bleeding (71.4%), and pelvic pain (57.4%).
• False-negative probabilities for endometrial cancer diagnoses were 3.8% at a 3-mm threshold, 9.5% at a 4-mm threshold, and 11.4% at a 5-mm threshold.
• Endometrial thickness thresholds derived from predominantly White populations may not be applicable to Black patients.

Interpretation:

Limitations:

• The study's retrospective design may limit the generalizability of the findings.
• The analysis is based on data from a specific population and timeframe.

Conclusion:

Sources:

• JAMA Oncology Study