Objective:

To evaluate the effects of topical autologous platelet-rich plasma (PRP) on postoperative pain and wound healing following tonsillectomy.

Approach:

Key Findings:

• Postoperative pain was lower in the PRP group with a mean difference of −0.8 points on the visual analog scale.
• Statistically significant pain differences were observed on postoperative days 1 through 8.
• Complete mucosal healing by day 14 occurred in 78% of PRP patients vs 59% of controls.
• Wound healing scores were better on postoperative days 7, 10, and 14 in the PRP group.
• Secondary hemorrhage occurred in 2% of PRP patients vs 5% in controls.

Interpretation:

Topical autologous PRP applied during tonsillectomy is associated with reduced postoperative pain and improved wound healing, suggesting it may enhance early recovery.

Limitations:

• Single-center design limits generalizability.
• Lack of age-stratified analyses.
• Inability to blind the operating surgeon during application.
• Not powered to detect differences in rare outcomes like hemorrhage.

Conclusion:

Topical autologous PRP may be a useful adjunct for enhancing early recovery after tonsillectomy.

Sources:

• American Journal of Otolaryngology
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