5 Key Takeaways

• 1

  Dogs share biochemical mortality markers with humans, as shown in a study analyzing 133 plasma metabolites in 937 companion dogs.

• 2

  Seventeen percent of the metabolites studied were linked to all-cause mortality, with 23 meeting statistical significance.

• 3

  In a follow-up period averaging 2.6 years, 104 dogs died, allowing for a quicker mortality analysis compared to human studies.

• 4

  Mortality associations for overlapping metabolites were consistent between dogs and humans 64% of the time across five studies.

• 5

  Specific metabolites linked to mortality in both species include higher pseudouridine and lower deoxycarnitine, indicating shared aging biology.