October 28, 2026 NUT carcinoma may defy typical staining patterns Two pulmonary cases highlight how limited squamous differentiation and variable keratin expression may complicate pathological diagnosis. MDSpire News
October 27, 2026 FDA expands talazoparib use in prostate cancer The combination with enzalutamide reduced the risk of radiographic progression or death by 52% . MDSpire News
October 23, 2026 FDA raises TMB threshold for pembrolizumab Traditional approval narrows eligibility for previously treated solid tumors after efficacy was not confirmed at lower biomarker levels. MDSpire News
October 22, 2026 STAT6 may aid diagnosis of giant pulmonary SFT Immunohistochemical testing confirmed a rare tumor despite low-grade histology, extensive local involvement, and suspected liver metastasis. MDSpire News
October 19, 2026 FDA approves dostarlimab for advanced rectal cancer The accelerated approval adds an immunotherapy option for patients with MSI-H/dMMR stage II/III disease. MDSpire News
October 15, 2026 AI may predict focal GBM recurrence Optical analysis of resection-margin tissue identified tumor infiltration as the strongest contributor to predictions of where glioblastoma later recurred. MDSpire News
October 14, 2026 FDA expands bladder cancer therapy approval The expansion offers another treatment option for patients with high-grade tumors following BCG failure. MDSpire News
September 28, 2026 ACS report: Lung cancer deaths plunge as survival doubles Lung cancer deaths fell by more than half among US males as smoking declined, earlier-stage diagnoses increased, and 5-year relative survival doubled. MDSpire News
September 25, 2026 FDA monthly preview: Key October decisions to watch Several FDA decisions across multiple specialties are expected this month. MDSpire News
September 24, 2026 FDA approves combo for advanced renal cell carcinoma Median progression-free survival was 15 months with the combination vs. 11 months with cabozantinib in the LITESPARK-011 trial. MDSpire News