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Conexiant chevron_right Psychiatry chevron_right FDA Clears Esketamine Monotherapy for Depression
FDA & Government News

FDA Clears Esketamine Monotherapy for Depression

"[Esketamine] is now available as a standalone treatment, meaning patients may experience improvements in depressive symptoms as early as 24 hours and at 28 days—without the need for daily oral antidepressants."

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  1. Esketamine nasal spray was approved as first monotherapy for treatment-resistant depression.
  2. 22.5% of patients treated with the agent achieved remission at week 4.
  3. Safety profile was consistent with real-world data.  
  4. Target neurotransmitter: glutamate.
  5. Administered to more than 140,000 patients worldwide.

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