4 Topic Commentaries

Neurogenic progression may falter in MDD

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  Maura Boldrini Dupont, MD, PhD

  Psychiatry, Neuroscience

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  Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons

  Turning neurogenesis back on may be a way to treat depression in some people by rewiring their hippocampus circuit.

  Source
• 

  Barry L. Jacobs, PhD

  Psychology, Neuroscience

  •

  Princeton University

  As soon as we showed that serotonin was important in neurogenesis, it occurred to me that neurogenesis might be important in recovery from depression.

  Source
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  Ronald S. Duman, PhD

  Psychiatry, Neuropharmacology

  •

  Yale School of Medicine

  The results of our study demonstrate that anti-depressants can reverse or block further loss of neurons in the hippocampus by increasing neurogenesis (new cell growth).

  Source
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  Andrew D. Pieper, MD, PhD

  Psychiatry, Neurology

  •

  University of Iowa Carver College of Medicine; Department of Veterans Affairs

  The P7C3 compounds showed potent antidepressant activity that was based on their neurogenesis-promoting properties.

  Source