5 Key Takeaways

• 1

  Prucalopride treatment for seven to ten days improved cognitive performance in patients with remitted recurrent depression.

• 2

  Improvements were noted in verbal learning, working memory, and facial expression recognition compared to placebo.

• 3

  The strongest effect was observed in verbal learning and memory, with patients recalling more words than those on placebo.

• 4

  Prucalopride was well tolerated, with similar rates of adverse effects compared to placebo, though decreased appetite was more frequent.

• 5

  The study's limitations include a small sample size and a focus on younger, predominantly female participants.