5 Key Takeaways

• 1

  Patients with schizophrenia exhibited a repulsive serial bias in working memory, contrasting with bipolar disorder patients who showed a mixed pattern.

• 2

  Healthy controls demonstrated an attractive bias, while patients with bipolar disorder had a weaker attractive bias compared to controls.

• 3

  Working memory precision was lower in schizophrenia patients than in bipolar disorder patients and healthy controls, indicating faster memory decline.

• 4

  The study suggests that serial bias could serve as a biomarker for treatment development, focusing on biologically defined subgroups.

• 5

  Findings indicate potential neurobiological overlap between some bipolar disorder patients and schizophrenia, challenging traditional diagnostic boundaries.