Lasers trigger pigmentation from past gold therapy
Background
Chrysiasis is a rare condition characterized by blue-gray pigmentation due to gold deposition, often seen in patients with a history of chrysotherapy. The occurrence of laser-induced chrysiasis is particularly uncommon, with fewer than 10 cases reported in the literature. Understanding the implications of past gold therapy is crucial for clinicians when considering laser treatments.
Data Highlights
| Patient | Age | Gold Therapy Duration | Laser Treatment | Improvement |
|---|---|---|---|---|
| 1 | 60 | 1989-1994 | 1064-nm Q-switched laser | 90% reduction |
| 2 | 70 | 36 years prior | 1064- and 532-nm picosecond lasers | Moderate improvement |
Key Findings
- Both patients developed grayish-blue pigmentation after laser treatments.
- Histopathologic findings showed dermal metallic deposits consistent with chrysiasis.
- Short-pulse laser exposure was associated with the pigmentation changes observed.
- A history of chrysotherapy should be considered before laser procedures.
Clinical Implications
Clinicians should obtain a thorough history of gold salt therapy in patients prior to administering short- or ultrashort-pulse laser treatments.
Conclusion
The cases illustrate the occurrence of pigmentation changes in patients with a history of gold therapy following laser treatments.
Related Resources & Content
- Mazzuco R, Journal of Cosmetic Dermatology, 2023 -- Lasers trigger pigmentation from past gold therapy
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