5 Key Takeaways

• 1

  Two patients developed laser-induced chrysiasis after receiving gold salt therapy for rheumatoid arthritis decades earlier.

• 2

  Both patients showed improvement in pigmentation after treatment with intense pulsed light and trichloroacetic acid peels.

• 3

  Histopathologic findings revealed dermal metallic deposits consistent with chrysiasis, characterized by blue-gray pigmentation.

• 4

  The mechanism of laser-induced chrysiasis may involve fragmentation of gold particles and alteration of light scattering.

• 5

  A history of gold salt therapy should be considered before short- or ultrashort-pulse laser procedures.