A JAMA Viewpoint argued that US regulatory frameworks have struggled to keep pace with the rapidly expanding market for injectable peptides promoted online for muscle growth, recovery, and antiaging. The authors noted that peptides now circulate through approved therapeutic markets, legal compounding pathways, and unregulated supply channels, blurring the line between medicine and enhancement. They highlighted limited human evidence, potential safety concerns, and growing awareness among adolescent boys and young men. The authors called for more coordinated regulatory, surveillance, research, and digital platform strategies to address emerging peptide use.

Source: JAMA