5 Key Takeaways

• 1

  This retrospective, single-center study included 176 surgically treated patients with Bethesda II benign thyroid cytology and postoperative histopathology.

• 2

  Postoperative malignancy was identified in 20 patients (11%), while 156 patients (89%) had benign findings.

• 3

  Malignancy was found in 32% of patients with TIRADS classifications of 4 or greater, compared with 7% of those with lower classifications.

• 4

  TIRADS classifications of 4 or greater were associated with about 5.7 times the adjusted odds of malignancy, and each additional year of age with about 8% lower odds.

• 5

  The authors cautioned that the 11% malignancy rate reflects a selected surgical population and should not be generalized to all patients with Bethesda II nodules.