New ddPCR Test Detects Lyme Disease More Accurately
MDSpire News
November 14, 2025
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Researchers at Dartmouth Hitchcock Medical Center developed ddPCR assays for more accurate Lyme disease diagnosis.
The assays detect genetic material from Borrelia species, including the primary Lyme disease agent, B. burgdorferi.
Three ddPCR assays were developed, targeting all Borrelia species, Lyme-causing species, and specifically B. burgdorferi.
The assays demonstrated high sensitivity and specificity, detecting as few as 5 to 10 bacterial cells.
Next steps include expanding testing to more cases and enhancing assay sensitivity, according to Dr. Huang.
This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.
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