Researchers Unveil Multiplex PCR for Endemic Fungi
MDSpire News
November 13, 2025
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Researchers at Indiana University developed a multiplex PCR assay to identify three serious endemic fungal infections.
The assay detects Histoplasma, Blastomyces, and Coccidioides directly from clinical specimens in a single run.
The new method bypasses slow culture processes and unreliable serology, improving diagnostic speed and accuracy.
The assay showed 100% agreement with standard testing in identifying isolates from 32 patient specimens.
Preliminary data indicate the assay may meet regulatory requirements for fungal identification, pending full validation.
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