5 Key Takeaways

• 1

  Over half of adults evaluated 11 to 18 months post-mpox diagnosis had at least one persistent physical sequela.

• 2

  The most common sequelae were mild appearance-related changes, including skin discoloration and scarring.

• 3

  Thirteen percent of participants reported functional complications, primarily involving anorectal and urinary symptoms.

• 4

  Nearly half of participants experienced ongoing social challenges, with significant effects on sexual performance reported.

• 5

  Persistent sequelae were linked to markers of more severe acute disease, particularly confluent lesions over 2 cm.